Epigenetics: How Your Lifestyle Literally Changes Your DNA

Sat Apr 30 2016 Go ahead and blame your parents. Its true, a majority of who you are and how you function was predetermined by the genetic material you inherited when your fathers sperm implanted in your mothers egg. Environmental factors critically influence us as well. Thus, for centuries scientist described human variability as genetic heritability + environmental influences. In other words, you = your genes + your lifestyle. But this all changed in 2003 when the human genome was finally mapped. Now, science tells us its possible to control your own genetic destiny in a small but meaningful way. If youre not happy with your genes, you can hire a DNA lifestyle coach to help you become who you want to be! Evolution and the Gene Pool Weve all heard sayings like only the strong survive. This concept, outlined by Charles Darwin, suggests the organisms best fit (strongest) for the environment will survive over time. The offspring of these animals are at an advantage, as they possess the physical traits best-suited for that environment (i.e. they inherit great genes). Animals lacking optimal genetic inheritance will need to adapt, or perish. Humans are no different. Our bodies were built to adapt to environmental stressors. Our cells constantly accrue damage during the normal living process. These malfunctioning cells need removal and replacement with identical, fully-operational replicas. We accomplish this maintenance by identifying the portion of our DNA (called a gene) that makes the damaged cell. The targeted gene is expressed, resulting in the building of the exact right cell. Change the expression and you literally change your DNA. A Look at Epigenetics Gene expression has received extensive scientific study over the last 3+ decades. However, only lately have scientists realized the expression of your genes changes throughout your lifetime (epigenetics). Its leading to more informed research about how to change your DNA. Epigenetics is arguably the hottest topic in Physiology right now, but the research is in its infancy and many important questions remain. Nonetheless, the available evidence clearly shows that lifestyle choices like exercise, nutrition, and sleep significantly affect the genes responsible for numerous physiological adaptations (e.g., energy utilization, mitochondrial density, etc.). Challenge Your Genetics, Change Your Lineage The idea that your exercise habits change the way your DNA is expressed was both shocking and exciting. Even more surprising was the realization that epigenetic changes are inherited by your offspring! A recent study provided the first evidence that exercise training regulates and changes the epigenetic profile in the sperm of healthy men. So, while part of you was predetermined, a part of your children is determined by your lifestyle. You were built to handle and adapt to challenges. Never forget that, and never stop challenging. You = your lifestyle. Your lifestyle = the genes your children inherit.